New coronal animal origin virus


China Wei Jian novel coronavirus pneumonia (COVID-19) joint investigation report was released by the State Council of China on February 29th. The novel coronavirus pneumonia is a kind of animal derived virus. According to the existing evidence, air transmission is not considered as the main mode of transmission. At present, the phylogenetic analysis of the whole genome gene sequence shows that bats seem to be the host of the virus, but the intermediate host has not been identified.
The novel coronavirus pneumonia is an animal derived virus intermediate host.
The novel coronavirus pneumonia virus is an animal derived virus. At present, the phylogenetic analysis of the whole genome gene sequence shows that bats seem to be the host of the virus, but the intermediate host has not been identified. China has carried out work in three important areas of animal traceability of the epidemic: ① carry out early investigation on the cases in Wuhan in December 2019; ② carry out environmental sampling on the South China seafood wholesale market and other markets; ③ carry out a detailed investigation on the sources and types of wild animals sold in the South China seafood wholesale market and the whereabouts of these animals after the closure of the market.
Main mode of transmission of virus: droplets and close contact
Novel coronavirus pneumonia is transmitted through droplets and close contacts between infected and infected persons without protection. No novel coronavirus pneumonia is reported. In addition, according to the existing evidence, air transmission is not considered as the main mode of transmission. However, in medical institutions, there may be the possibility of air transmission due to aerosol generated by medical operations. Novel coronavirus pneumonia has been confirmed in novel coronavirus pneumonia. However, according to available evidence, fecal oral transmission seems not to be the main mode of transmission of new crown pneumonia, and its status and role in the transmission of new crown pneumonia virus remains to be determined.
Interpersonal communication in China’s novel coronavirus pneumonia is mainly limited to family and community communication is very limited.
In China, the novel coronavirus pneumonia is mainly transmitted in the family, the report shows. A total of 1308 cases (1836 cases in total) were reported in 344 cases of clustering in Guangdong and Sichuan provinces, most of which (78% – 85%) occurred in family members. However, the preliminary study in Guangdong estimated that the second generation recurrence rate of family members was about 3-10%.
In addition, up to now, the vast majority of cases are from or directly related to Wuhan or Hubei. Community communication is very limited. Most of the local cases come from clustered cases, most of which occur in families.
Almost all of the novel coronavirus pneumonia is susceptible to most mild cases and can be cured.
Because the novel coronavirus pneumonia is a newly discovered pathogen, the population is generally immune to deficiency. According to the epidemiological characteristics observed in China at present, almost everyone is susceptible to infection, and further study is needed to determine whether they have immunity after infection. Patients with novel coronavirus pneumonia usually have symptoms for 5-6 days (average incubation period of 5-6 days, range 1-14 days). Most of them are mild and can recover. Severe and high-risk groups are over 60 years of age.
“The bravest, most flexible and most active prevention and control in history”
The report points out that in the face of this unprecedented virus, China has taken the bravest, most flexible and most active prevention and control measures in history.
China has adopted novel coronavirus pneumonia measures, which effectively cut off the transmission of virus and provide important experience for coping with the new crown pneumonia in the world. Although community-based transmission has occurred in other areas of Hubei Province, and other provinces with imported cases also have family clustering epidemics, these unique and unprecedented measures taken by China have completely reversed the escalating epidemic situation in Hubei and other regions.
The novel coronavirus is a new pathogen that is highly infectious and spread rapidly. It will have public health problems and economic and social impacts in any environment, the team said. It is neither SARS nor influenza. It is not enough to prevent the spread, reduce the disease and save lives to construct the understanding of the virus and formulate the prevention and control measures based on the two known pathogens.
China China novel coronavirus pneumonia joint expert inspection group is composed of 25 experts from China, Germany, Japan, Korea, Nigeria, Russia, Singapore, the United States and WHO, covering epidemiology, virology, clinical management, public health and other fields. The foreign leader of the joint inspection team is Dr. Bruce elwald of the World Health Organization, and the Chinese leader is Dr. Liang Wannian.
From February 16 to 24, the joint investigation team carried out investigation and research in China for 9 days. In four provinces of Beijing, Hubei, Guangdong and Sichuan, we visited designated hospitals, fangcang hospitals and grass-roots communities, including relevant departments and disease control institutions, etc., and had in-depth discussions and exchanges with government officials, health and epidemic prevention workers, medical personnel, community doctors and residents.
The report of the joint investigation group is mainly divided into six aspects: virus, outbreak, transmission dynamics, disease process and severity, China’s response measures and knowledge limitations.